https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19948 Wed 27 Jul 2022 13:58:56 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45150 Wed 26 Oct 2022 19:29:23 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36475 18 y. Where possible, studies were pooled for meta-analysis using RevMan 5.2. The principle summary measure was the mean difference between groups calculated using the random-effects model. Results: Eleven eligible crossover and 1 parallel trial were identified with a total of 299 participants [weighted mean ± SD age: 38 ± 3 y; weighted mean ± SD body mass index (kg/m²): 24 ± 2]. All studies were pooled for the meta-analysis. Diets enriched with MCFAs led to significantly higher high-density lipoprotein (HDL) cholesterol concentrations than diets enriched with LCSFAs (0.11 mmol/L; 95% CI: 0.07, 0.15 mmol/L) with no effect on triglyceride, low-density lipoprotein (LDL) cholesterol, and total cholesterol concentrations. Consumption of diets rich in MCFAs significantly increased apolipoprotein A-I (apoA-I) concentrations compared with diets rich in LCSFAs (0.08 g/L; 95% CI: 0.02, 0.14 g/L). There was no evidence of statistical heterogeneity for HDL cholesterol, apoA-I, and triglyceride concentrations; however, significant heterogeneity was observed for the total cholesterol (I² = 49%) and LDL cholesterol analysis (I² = 58%). Conclusion: The findings of this research demonstrate a differential effect of MCFAs and LCSFAs on HDL cholesterol concentrations. Further investigations are warranted to elucidate the mechanism by which the lipid profile is altered. This trial was registered at www.crd.york.ac.uk/PROSPERO as CRD42017078277.]]> Wed 24 Nov 2021 15:51:06 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33436 Wed 17 Nov 2021 16:28:46 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35600 Wed 11 Sep 2019 17:41:44 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10917 Wed 11 Apr 2018 16:57:16 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17516 Wed 11 Apr 2018 16:36:34 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1871 Wed 11 Apr 2018 15:04:47 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30241 Wed 11 Apr 2018 14:56:00 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:3022 Wed 11 Apr 2018 13:23:31 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:15726 Wed 11 Apr 2018 12:38:03 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48772 Wed 05 Apr 2023 14:02:43 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27931 Wed 02 Oct 2019 13:19:54 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36804 Tue 07 Jul 2020 10:02:42 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24083 Thu 04 Nov 2021 10:38:19 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1947 Sat 24 Mar 2018 08:33:19 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1886 Sat 24 Mar 2018 08:31:18 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:2951 Sat 24 Mar 2018 08:30:59 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1239 Sat 24 Mar 2018 08:28:34 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16994 Sat 24 Mar 2018 08:00:13 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16973 Sat 24 Mar 2018 07:55:26 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24117 Sat 24 Mar 2018 07:11:43 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45764 Sat 05 Nov 2022 12:13:58 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47536 Mon 23 Jan 2023 12:22:36 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42483 p = 1.1 x 10⁻⁸). By contrast, the causal effect of LDL-C was much weaker for IS (OR 1.12, 95% CI 0.96−1.30, p = 0.14; p for heterogeneity = 2.6 x 10⁻³) and, in particular, for cardioembolic stroke (OR 1.06, 95% CI 0.84−1.33, p = 0.64; p for heterogeneity = 8.6 x 10⁻³) when compared with that for CHD. Conclusions: In contrast with the consistent effects of LDL-C-lowering therapies on IS and CHD, genetic variants that confer lifelong LDL-C differences show a weaker effect on IS than on CHD. The relevance of etiologically distinct IS subtypes may contribute to the differences observed.]]> Fri 26 Aug 2022 13:56:54 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53055 Fri 17 Nov 2023 11:47:02 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35613 Fri 13 Sep 2019 15:01:50 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46137 n = 149). Assessments occurred at 20 months post-stroke, using the Mini Mental State Examination and serum blood levels of cholesterol, low density lipoprotein, high density lipoprotein and serum triglycerides. Results: Hierarchical linear regression showed that only acute functional impairment significantly contributed to long-term cognitive impairment in stroke survivors. Only 12% of the sample showed healthy cholesterol levels while the remaining patients showed borderline or high cholesterol levels. In terms of BMI, only 2% of the sample were underweight, 38% were within healthy range and 26% were overweight/obese. Only eight women and four men were smokers, therefore our sample of smokers was likely too small to detect any differences between smokers and non-smokers in regard to cognitive outcomes. Conclusion: Serum cholesterol, low density lipoprotein, high density lipoprotein, serum triglycerides, BMI or smoking status did not influence cognitive outcomes in older stroke surviving individuals. These findings suggest that modification of these factors may not influence cognitive outcomes in stroke-surviving individuals however should be interpreted as preliminary given limitations in the current study.]]> Fri 11 Nov 2022 16:31:53 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47883 Fri 03 Feb 2023 16:00:04 AEDT ]]>